Gonal F-300 IU Pen

Gonal-F 300 IU pen is a pre-filled, multi-dose FSH injection used in IVF treatment to stimulate follicle growth in the ovaries. It contains follitropin alfa, a recombinant form of follicle-stimulating hormone (FSH) — the same hormone your pituitary gland produces naturally. At Fast IVF, you can order Gonal-F 300 IU pen at a fraction of the US retail price.

What Does Gonal-F 300 IU Pen Do?

During an IVF cycle, your ovaries need to produce multiple eggs. Gonal-F 300 IU stimulates the ovaries to develop several follicles at once. More follicles mean more eggs available for retrieval, which improves your chances of a successful cycle.

Your doctor will decide the exact dose and timing based on your age, weight, and IVF protocol. Treatment typically starts on day 2 or 3 of your menstrual cycle and runs for 8 to 14 days.

How to Use the Gonal-F 300 IU Pen

The pen is injected subcutaneously — just below the skin, usually in the abdomen. Each click of the dial delivers a precise dose of follitropin alfa, so theres no need to measure or mix. It’s one of the easiest IVF injections to self-administer.

If you’re new to self-injections, check our step-by-step injection instruction videos and our guide on how to avoid bruising after IVF injections.

Does Gonal-F 300 Need to Be Refrigerated?

Yes. Gonal-F 300 IU pen must be stored in the refrigerator (2°C–8°C) until first use. Once opened, it can be kept at room temperature (below 25°C) for up to 28 days. See our full IVF medication refrigeration guide for storage tips across all IVF meds.

Is Gonal-F 300 IU Used With Other Medications?

Yes, most IVF protocols combine Gonal-F with other medications. It’s often used alongside Menopur for enhanced stimulation. Many clinics also prescribe a GnRH antagonist like Cetrotide or Orgalutran to prevent premature ovulation. At the end of stimulation, an HCG trigger shot like Ovitrelle is used to trigger egg release.

Read more about why clinics use Gonal-F and Menopur together.

Who Should Avoid Gonal-F?

Talk to your doctor before using Gonal-F 300 if you have ovarian cysts or tumors, thyroid or adrenal issues, or a history of blood clots. It may also increase the chance of a multiple pregnancy (twins or triplets). Your reproductive endocrinologist will weigh the benefits and risks for your specific situation.

For a broader overview of all IVF medications used in a cycle, visit our medications hub.

Gonal-F 300 IU Pen Price — What Does It Cost?

In the US, Gonal-F 300 IU pen can cost $350–$500 without insurance. At Fast IVF, we source European-brand Gonal-F at significantly lower prices. Many patients save hundreds of dollars per pen compared to US retail. You can also get the Gonal-F 450 IU pen or Gonal-F 900 IU pen depending on your prescribed dose.

See all FSH options in our follitropin alfa / FSH category, or get a free personalized quote for your full medication list.

Frequently Asked Questions

What is Gonal-F 300 IU pen used for?

Gonal-F 300 IU pen is used in IVF and other assisted reproduction treatments to stimulate the ovaries to grow multiple follicles. Each follicle may contain an egg that can be retrieved and used in the fertilization process.

How many injections does one Gonal-F 300 IU pen contain?

One pen contains 300 IU of follitropin alfa. The number of injections depends on your daily dose — for example, at 75 IU per day, one pen provides about 4 injections. Your doctor will prescribe the right quantity for your full cycle.

Is Gonal-F 300 the same as Follistim?

No. Gonal-F contains follitropin alfa, while Follistim contains follitropin beta. Both are recombinant FSH medications used in IVF, but they are made by different manufacturers and have slightly different formulations. Fast IVF also carries Puregon, which is the European equivalent of Follistim.

Can I order Gonal-F 300 IU pen online?

Yes. Fast IVF ships European-brand Gonal-F to patients in the US and internationally. A valid prescription from your IVF clinic is required. Orders typically ship within 3–5 business days once your prescription is verified.

What is the difference between Gonal-F 300, 450, and 900 IU pens?

The difference is the total amount of medication in each pen. The dose your doctor prescribes per injection stays the same — a higher IU pen just lasts more days before running out. Choosing the right pen size can reduce waste and lower your overall Gonal-F cost.

According to the FDA, follitropin alfa is an approved gonadotropin indicated for controlled ovarian stimulation in assisted reproductive technology programs.