

ORGALUTRAN 0.25MG/0.5ML
| Other Names: | Ganirelix |
| Active Ingredient: | Ganirelix |
| Dosage: | Orgalutran 0.25mg/0.5mL |
| Maker: | Organon |
What Is Ganirelix Organon (Orgalutran)?
Ganirelix Organon (sold under the brand name Orgalutran) is prescribed to prevent premature LH surges in women undergoing ovarian stimulation. Your fertility specialist will use this medication alongside other fertility drugs like Gonal-F or Menopur to optimize egg development and retrieval timing.
How Does Orgalutran Work in Fertility Treatment?
Ganirelix Organon works differently than older GnRH agonist protocols. Instead of initially stimulating hormone production before suppressing it, Orgalutran immediately blocks GnRH receptors. This prevents your body from releasing eggs too early, giving your fertility team better control over the exact timing of egg retrieval.
Your doctor or nurse will tell you when to start Orgalutran injections – typically around day 5 or 6 of stimulation. You’ll continue daily injections until your trigger shot, which is usually administered 34-36 hours before your egg retrieval procedure.
How to Administer Ganirelix Injections
Orgalutran is administered subcutaneously, usually in the lower abdomen or upper thigh. Your healthcare provider will show you the proper injection technique, or you can watch our detailed instructional videos for step-by-step guidance on avoiding bruising after injections.
Most patients find ganirelix injections relatively easy to self-administer. The pre-filled syringes come ready to use, and the needle is small and thin for patient comfort.
Orgalutran vs Cetrotide: What’s the Difference?
Both Orgalutran and Cetrotide are GnRH antagonists that work the same way in your body. The main differences are manufacturer and cost. Our detailed ganirelix vs cetrotide comparison breaks down everything you need to know.
| Feature | Orgalutran (Ganirelix) | Cetrotide |
|---|---|---|
| Active Ingredient | Ganirelix Acetate | Cetrorelix Acetate |
| Manufacturer | Organon | Merck Serono |
| Dosage | 0.25mg/0.5mL | 0.25mg |
| Format | Pre-filled syringe | Powder for reconstitution |
| Ease of Use | Ready to inject immediately | Requires mixing before injection |
| Effectiveness | Clinically equivalent | Clinically equivalent |
Who Should Not Use Orgalutran?
Ganirelix Organon is contraindicated in the following situations:
- Known hypersensitivity to ganirelix acetate or any components
- Known hypersensitivity to GnRH or any GnRH analog medications
- Known or suspected pregnancy
- Breastfeeding (consult your doctor)
Always inform your fertility specialist about any medications you’re taking and any allergies you have before starting Orgalutran.
Frequently Asked Questions About Ganirelix Organon
When do I start taking Orgalutran during fertility treatment?
Most patients start Orgalutran injections on day 5 or 6 of ovarian stimulation, once follicles reach a certain size. Your fertility clinic will monitor your progress through ultrasounds and blood tests to determine the exact start date based on your individual response.
Does Orgalutran need to be refrigerated?
Yes, ganirelix should be stored in the refrigerator at 2-8°C (36-46°F) until use. Learn more about proper storage requirements for fertility medications to maintain their effectiveness.
How many days will I take Orgalutran injections?
The typical treatment duration is 4-6 days, but this varies based on your individual protocol and how quickly your follicles develop. You’ll continue daily injections until your healthcare team determines its time for your trigger shot.
Can I switch between Orgalutran and Cetrotide during my cycle?
While both medications work similarly, its best to stay with one GnRH antagonist throughout your cycle unless your doctor specifically recommends switching. Consistency helps your medical team track your response accurately.
What are common side effects of ganirelix?
Most patients experience minimal side effects from Orgalutran. The most common reactions include mild injection site redness, headaches, or nausea. Serious allergic reactions are rare but require immediate medical attention if they occur.
Orgalutran is available through Fast IVF with guaranteed on-time delivery. All medications are sourced from licensed European pharmacies and shipped with proper temperature control to ensure quality and effectiveness.
