What Is Human Chorionic Gonadotropin (HCG)

HCG (hormone called human chorionic gonadotropin) helps a woman’s fertilized egg continue to develop. It is commonly used as an infertility treatment. The fertilized egg is attached to the uterine wall by the placenta following the union of sperm and ovum in the fallopian tube. The placenta’s cells begin to secrete human chorionic gonadotropin after implantation. Essentially, it is a glycoprotein with a molecular mass of 25.7 kDa and 237 amino acids.

How hCG injections increase women’s fertility

During treatment cycle, hCG is injected into women to encourage ovulation. Because it causes ovulation to begin roughly 36 hours later, this is frequently referred to as a trigger shot. HCG aids in egg maturation, preparing them for fertilization.

An hCG injection aids egg maturation in in-vitro fertilization (IVF) patients before the eggs are fertilized in a lab. It is frequently employed in all fertility procedures, including IVF and IUI (intrauterine insemination).

Patients who are attempting a range of infertility treatments, each of which has a variable success rate, employ HCG trigger shots. Despite the fact that hCG can increase conception rates for the majority of procedures, including embryo transfers, there is no simple way to determine the success rate.

How hCG injections increase male fertility

LH, a hormone that raises testosterone levels, is mimicked by HCG. Additionally, because testosterone is essential for the creation of sperm, Experts note that hCG may be utilized to increase fertility in men who have low testosterone levels and insufficient sperm counts.

For guys with hypogonadotropic hypogonadism (HH), a disorder in which the body does not create enough sex hormones, this can be very beneficial.

According to studies, hCG can increase sperm levels in roughly 25% of men with HH, making it easier for them to conceive.

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